By E. Lindh (Eds.)
For a few years, biochemical assessments were universal for the analysis, type, and tracking of bone and connective tissue sickness. even if, shortcomings by way of the specificity and sensitivity of such assessments have brought on continuous wondering approximately their scientific usefulness. This ebook, in accordance with a gathering prepared together through the collage of Uppsala and Pharmacia Diagnostics AB, studies our present realizing of easy bone and connective tissue biochemistry and the scientific position of biochemical markers particular to comparable ailments, with particular connection with rheumatoid a. Read more...
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Foremost has been the paucity of direct methods to measure it with sufficient specificity and sensitivity in the easily available body fluids and tissue samples. Even where H A is a b u n d a n t , glycoproteins and other saccharides interfere with its measure ment as either glucuronic acid or acetylglucosamine unless complex steps are taken to separate it beforehand. This problem is compounded by the fact that the levels of H A in plasma and urine are even lower than those of other glycosaminoglycans.