Analytical Determination of Nicotine and Related Compounds by J.W. Gorrod, P. Jacob III

By J.W. Gorrod, P. Jacob III

This e-book offers for the 1st time a unmarried complete resource of knowledge at the analytical chemistry of nicotine and comparable alkaloids. The editors have introduced jointly scientists from academia and the tobacco to explain the cutting-edge of the chemistry and analytical equipment for size of nicotine. either the scope and element of the ebook are extraordinary. Chapters describe the historical past, pharmacology and toxicology of nicotine, the biosynthesis of nicotine and different alkaloids within the tobacco plant, the overall chemistry of nicotine and the analytical methodologies which have been used to degree nicotine and comparable alkaloids in organic specimens, in tobacco and pharmaceutical items and in tobacco smoke. there's additionally a accomplished overview of the chemistry and toxicology of nicotine-derived nitrosamines, a massive category of tobacco cancer causing agents.

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40 Hobbs MC, Yeoman MM. Biotransformation of nicotine to nornicotine by cell suspensions of Nicotiana tabacum L. cv. Wisconsin-38. , 1991: 119; 477-482. 41 Botte M, Mabon F, Mouillour ML, Robins RJ. Biosynthesis of nornicotine in root cultures of Nicotiana alata does not involve oxidation at C-5' of nicotine. Phytochemistry, 1997:117; 117-222. 42 Fannin FF, Bush LP. Nornicotine accumulation in nicotine-fed detached leaves of N. glauca, N. glauca/N, tabacum grafted plants and N. tabacum X N. glauca hybrids.

Annu. Rev. , 1988: 42; 575-606. 51 Chilton M-D, Tepfer D, Petit A, David C, Casse-Delbart F, Temp6 J. Agrobacterium rhizogenes inserts T-DNA into the genomes of host plant root cells. Nature, 1982: 295; 432-434. 52 White FF, Taylor BH, Huffman GA, Gordon MP, Nester EW. Molecular and genetic analysis of the transferred DNA regions of the root-inducing plasmid of Agrobacterium rhizogenes. J. , 1985: 164; 33-44. 40 Biosynthesis of Nicotine and Related Compounds 53 Slightom JL, Durand-Tardif M, Jouanin L, Tepfer D.

Not as the result of removing apical dominance, but rather as the result of leaf damage. Such increases are thought to confer a survival advantage on the plant against herbivory. Evidence has appeared that nicotine production is probably only part of a portfolio of defensive responses by the genus Nicotiana, comprising (at least) "... alkaloids, phenolics, proteinase inhibitors, PR (pathogenesis response) proteins, and sesquiterpenoid phytoalexins" (see [81]). An engaging account of these and related induced responses in other plants is given in 'Induced Responses to Herbivory' [82].

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