Advances in Understanding Aortic Diseases by Geoffrey D. Rubin (auth.), Teruhisa Kazui M.D., Shinichi

By Geoffrey D. Rubin (auth.), Teruhisa Kazui M.D., Shinichi Takamoto M.D. (eds.)

Following the 1st overseas symposium ever held in Asia on Advances in realizing Aortic ailments (AUAD), this quantity of lawsuits comprises the papers offered in either the oral and poster classes. The eighth AUAD symposium enormously contributed to the knowledge of aortic illnesses, particularly in Asia. Aortic ailments, particularly thoracic aortic ailments, are extra universal in Japan than in Western international locations, which provides extra value to this compilation that covers contemporary advancements and advances in thoracic aortic surgical procedure and its results. Divided into lectures, panel discussions, symposiums, and poster periods, the e-book comprises, between different issues, advances in imaging and prognosis with 3D-CT, MRS, and US; state of the art fix of the thoracic aorta; novel features of aortic root alternative; reconstruction; and prosthetic graft surgical procedure. This necessary selection of paintings presents the reader with an elevated wisdom and realizing of aortic illnesses not just in Japan yet worldwide.

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1007/978-4-431-99237-0_6, © Springer 2009 29 30 R. Deb et al. Introduction The prevalence of aneurysmal disease is increasing in the western world and in the UK currently accounts for 8000 deaths annually. Most aneurysm related deaths are as a result of rupture of previously undetected asymptomatic aneurysms, a diagnosis which carries an overall mortality of approximately 80% [1]. There are also significant cost implications for the local health service [2–3]. AAA screening has been shown to reduce mortality, as well as be cost-effective [2, 4–5] and has resulted in national and local ultrasound based programmes.

AAA screening has been shown to reduce mortality, as well as be cost-effective [2, 4–5] and has resulted in national and local ultrasound based programmes. AAA’s primarily affect middle aged and elderly male smokers, and as such there is an increased prevalence of atherosclerosis and other associated cardiovascular pathologies in this population [6]. The majority of patients undergoing vascular surgery have one or more cardiac risk factors, with 20% deemed high-risk as a result of significant stress induced ischemia [7].

Yoshimura et al. Introduction Abdominal aortic aneurysm (AAA) is a common disease that is characterized by chronic inflammation and degradation of extracellular matrix (ECM) by proteolytic enzymes, such as matrix metalloproteinases (MMPs), and eventually progresses to aneurysmal rupture with a high mortality [1]. Because most of patients with AAA have no symptoms until the catastrophic events of the rupture, main purpose of treatment for patients with AAA is to prevent the aneurysmal rupture, thereby improving their prognosis.

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