Advances in Cancer Research, Vol. 61 by George F. Vande Woude (ed.), George Klein (ed.)

By George F. Vande Woude (ed.), George Klein (ed.)

Quantity sixty one of "Advances in melanoma examine" contains insurance of the next: molecular methods to melanoma remedy, radiation resistance, melanoma prevention examine trials, mammalian gene amplification, retinoblastoma gene functionality, molecular genetic foundation of breast melanoma, and tumour advertising through okadaic acid classification compounds.

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Weinstein, I. B. (1991). Cancer R u . 51, 5080s-5085s. Willett, W. C. (1990). Med. Oncol. Tumor Pharmacother. 7 , 93-97. Ziegler, R. G. (1991). A m . J . Clin. Nutr. 53, 251s-259s. This Page Intentionally Left Blank MOLECULAR GENETIC CHANGES IN HUMAN BREAST CANCER Marc J. van de Vijver Department of Pathology, State University Leiden, Postbus 9603, 2300 RC Leiden. The Netherlands 1. Introduction 11. Clinicopathological Aspects of Breast Cancer A. Normal Breast Histology B. Histologic Types of Breast Cancer C.

And Tong, T. (1992). ]. Clin. 2(1), 19-38. Cohen, L. , Kendall, M. , ef al. ]. Natl. Cancer Inst. 83,496-500. De Cosse, J. ,and Lesser, M. L. ]. Natl. Cancer Inst. 81, 1290-1297. Deschner, E. , and Lynch, H. T. (1988). Cancer 61,2286-2290. , and Redmond, C. ]. Natl. Cancerlnst. 83, 1278-1280. , Shekelle, T. , Crique, M. , Rossof, A. , Paul, 0. (1985). Lancet 1, 307-309. , ef al. (1982). Lancet 2, 710-712. Greenwald, P. (1989). In “Principles and Practice of Oncology” (V. T. Devita, S. Hellman, and S.

The lobular and ductal structures are embedded in a myxoid, specialized stroma. T h e larger ducts all come together in a segmental duct; these segmental ducts all have a separate ending in the nipple. T h e breast contains approximately 15 segments, which do not have sharply defined anatomical borders. TYPES OF BREAST CANCER B. , malignant tumors of the epithelium, are the most frequent. Other cancers, for instance, sarcomas and lymphomas of the breast, d o occur, but will not be discussed here; these rare tumors have also not been considered in the genetic studies of breast cancer.

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